最近”低酸素”ネタが少ないような気がしています。
毎週火曜日の夕方journal clubを一階の皆さんとやっています（ぼくらは三階）。
二年以上前からやっていますが、ほぼ毎週続いていますね。これはこれですごい事です。
この４月以降読んだ論文を紹介しておきます。
この順番に読んだ訳ではありません、念のため。
これからこのJCで読んだ論文を"paper of the week" として紹介していきます。
Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs) -- Peyssonnaux et al. 117 (7): 1926 -- Journal of Clinical Investigation
Radiation and inhibition of angiogenesis by canstatin synergize to induce HIF-1{alpha}-mediated tumor apoptotic switch -- Magnon et al. 117 (7): 1844 -- Journal of Clinical Investigation
Differential Regulation of Hypoxia-Inducible Factor-1 through Receptor Tyrosine Kinase Transactivation in Vascular Smooth Muscle Cells -- Lauzier et al. 148 (8): 4023 -- Endocrinology
Mammalian Tumor Suppressor Int6 Specifically Targets Hypoxia Inducible Factor 2{alpha} for Degradation by Hypoxia- and pVHL-independent Regulation -- Chen et al. 282 (17): 12707 -- Journal of Biological Chemistry
HIF-1 Inhibits Mitochondrial Biogenesis and Cellular Respiration in VHL-Deficient Renal Cell Carcinoma by Repression of C-MYC Activity Cancer Cell -- Zhang et al.
Oncogene - Abstract of article: HIF-1 and NF-[kappa]B-mediated upregulation of CXCR1 and CXCR2 expression promotes cell survival in hypoxic prostate cancer cells
The transcription factor HIF-1{alpha} plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis -- Lum et al. 21 (9): 1037 -- Genes and Development
Regulation of HIF-1α Stability through S-Nitrosylation Molecular Cell -- Li et al.
HIF-1 Regulates Cytochrome Oxidase Subunits to Optimize Efficiency of Respiration in Hypoxic Cells Cell -- Fukuda et al.
HIF-2α Promotes Hypoxic Cell Proliferation by Enhancing c-Myc Transcriptional Activity Cancer Cell -- Gordan et al.
The Ternary Complex Factor Net Is Downregulated by Hypoxia and Regulates Hypoxia-Responsive Genes -- Gross et al. 27 (11): 4133 -- Molecular and Cellular Biology
Hypoxia-inducible Factor 1{alpha} Is Regulated by the Mammalian Target of Rapamycin (mTOR) via an mTOR Signaling Motif -- Land and Tee 282 (28): 20534 -- Journal of Biological Chemistry
Hypoxia-inducible factor 1{alpha} stabilization by carbon monoxide results in cytoprotective preconditioning -- Chin et al. 104 (12): 5109 -- Proceedings of the National Academy of Sciences